In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with.
When used intravenously, the following procedures should be undertaken to reduce the possibility of venous thrombosis, phlebitis, local irritation, swelling, and, rarely, vascular impairment; the solution should be injected slowly, taking at least one minute for each 5 mg (1 mL) given; do not use small veins, such as those on the dorsum of the hand or wrist; extreme care should be taken to avoid intra-arterial administration or extravasation.
When benzodiazepines and opioids are combined, the potential for benzodiazepines to significantly worsen opioid-related respiratory depression exists.
Diazepam is a benzodiazepine that is widely used orally as an anxiolytic agent and muscle relaxant. Intravenous forms of diazepam are used for acute severe agitation, as a premediation for anesthesia, a sedative for minor surgery or invasive procedures, and for treatment of status epileptus or severe recurrent seizures.
A liver biopsy showed changes typical of drug induced liver disease and the pattern of enzyme elevations and biopsy did not suggest viral hepatitis, serological testing for which was not available at the time. Causality assessment can only rank this example as a “possible” case of diazepam induced liver injury. In view of the wide scale use of diazepam, instances of hepatic injury are very rare, and no cases of severe, prolonged, persistent or fatal liver injury from diazepam have been published.
Diastat (DYE-ah-stat) is the brand name used in the United States and Canada for the seizure medicine with the generic name diazepam (dye-az-eh-pam). It is available in a gel form that is inserted into the patient's rectum to stop a cluster of repeated seizures. Similar products are available in the UK and other countries.
2017. Epilepsy Foundation of America, d/b/a Epilepsy Foundation, is a non-profit organization with a 501(3) tax-exempt status.
Some of the information may differ in other countries.
Throw away any medication that is outdated or no longer needed. Sometimes when a person takes this medicine long-term or in large amounts, their body may get used to this drug making the drug less effective or helpful. You should never stop taking this medication without talking to your doctor. not the bathroom). In most patients, lorazepam is usually prescribed for a period of 4-6 months, though at times your doctor may decide to keep you on the medication for a longer period of time.
Diazepam works by affecting the way certain substances in your brain (called neurotransmitters) pass messages to your brain cells. It has a calming effect.
If you buy any medicines check with a pharmacist that they are safe to take with your other medicines.
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For these reasons, before you start taking diazepam it is important that your doctor knows:.
Diazepam is used to relieve symptoms of anxiety and alcohol withdrawal. This medicine may also be used to treat certain seizure disorders and help relax muscles or relieve muscle spasm. Diazepam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants.
This medicine is available only with your doctor's prescription.
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Diazepam is used to relieve symptoms of anxiety and alcohol withdrawal. This medicine may also be used to treat certain seizure disorders and help relax muscles or relieve muscle spasm.
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Portions of this document last updated: March 01, 2017.
Diazepam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.
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